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Xyzal (Montelukast)

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Xyzal works by reducing and preventing swelling and inflammation in your lungs. It is used to prevent the symptoms of asthma such as tightness in your chest, wheezing, breathlessness and coughing.

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Also known as: Montelukast


Xyzal (montelukast) is a leukotriene (loo-koe-TRY-een) inhibitor. Leukotrienes are chemicals your body releases when you breathe in an allergen (such as pollen). These chemicals cause swelling in your lungs and tightening of the muscles around your airways, which can result in asthma symptoms.

Xyzal is used to prevent asthma attacks in adults and children as young as 12 months old. Xyzal is also used to prevent exercise-induced bronchoconstriction (narrowing of the air passages in the lungs) in adults and children who are at least 6 years old.

Xyzal is also used to treat symptoms of year-round (perennial) allergies in adults and children who are at least 6 months old. It is also used to treat symptoms of seasonal allergies in adults and children who are at least 2 years old.

Xyzal is used for allergies, only after other treatments have failed.

If you already take Xyzal to prevent asthma or allergy symptoms, do not use an extra dose to treat exercise-induced bronchoconstriction.


Asthma: - Adults (15 years of age and older): 10 mg a day. - Children (6 to 14 years of age): 5 mg a day. - Children (2 to 5 years of age): 4 mg a day. Xyzal should be taken once a day in the evening. Exercise-Induced Bronchoconstriction (EIB): - Adults (15 years of age and older): 10 mg a day. - Children (6 to 14 years of age): 5 mg a day. - Children (2 to 5 years of age): 4 mg a day. For prevention of EIB, Xyzal should be taken at least 2 hours before exercise. Do not take more than one dose in 24 hours. Allergic Rhinitis: - Adults (15 years of age and older): 10 mg a day. - Children (6 to 14 years of age): 5 mg a day. - Children (2 to 5 years of age): 4 mg a day. For allergic rhinitis, Xyzal should be taken once a day. Patients with both asthma and allergic rhinitis should take only one Xyzal dose daily in the evening. Pediatric patients are advised to take chewable tablets.


If you overdose Xyzal and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Xyzal overdosage: stomach pain, agitation, insomnia, thirst, migraine, vomiting.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Keep your tablets in the blister pack until it is time to take them. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take the Xyzal if you are allergic to Montelukast or any of the other ingredients of this medicine. Do not use the tablets to treat an acute asthma attack, including Status Asthmaticus. Do not use the drug if you suffer from severe kidney failure. Do not combine the medication with drugs which induce the CYP450 enzyme system (phenobarbital and rifampin), as they may decrease the effects of Montelukast. Do not use the medication if you have a phenylketonuria, as Xyzal contains phenylalanine. Do not take the medication tablets during pregnancy or while breastfeeding without consulting your doctor. Avoid drinking alcohol while taking Xyzal tablets, as it may cause excessive drowsiness. Do not give this medicine to children less than 2 years of age.

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